Carbonnelle et al. 2002 (30)
|
Chlorinated-pool (NCl3 mean concentration: 490
µg/m3) for recreational swimmers.
Chlorinated-pool (NCl3 mean concentration: 355
µg/m3) Vs copper/silver pool for trained
swimmers
|
Serum SP-A, SP-B and CC16
|
CC16 was not increased in recreational swimmers
In trained swimmers CC16 peaked immediately after strenuous exercise,
both in the copper/silver and in the chlorinated pools
SP-A and SP-B were unaffected by strenuous exercise in the
copper/silver pool
SP-A and SP-B were significantly increased in a time-dependent manner
in recreational and trained swimmers attending the chlorinated-pool
|
Carbonnelle et al. 2008 (91)
|
Chlorinated-pool (NCl3 concentration: 160-280
µg/m3 ) Vs copper/silver-pool
(NCl3 <20 µg/m3)
|
FeNO; serum SP-A, SP-B, CC16, KL-6
|
FeNO increased in the copper/silver pool, whereas it did not change in
the chlorinated-pool, suggesting that chlorination might inhibit
NO-induced vasodilation in exercise
Serum pneumoproteins were unchanged excepted SP-A which decreased
after exercise in the chlorinated pool (P < 0.05)
|
Font-Ribera et al. 2010 (92)
|
Chlorinated indoor pool
|
FeNO; serum SP-D and CC16; 8-isoprostane, several cytokines* and VEGF in
EBC
|
CC16 slightly increased after a swimming session
No significant changes in lung function, SP-D, 8-isoprostane,
cytokines, or VEGF.
|
Fernández-Luna et al. 2013 (93)
|
Chlorinated-pool Vs ozone-treated pool
|
Serum SP-D and CC16
|
No change was observed in lung function and SP-D in swimmers attending
both pools
CC16 was significantly increased in subjects attending the
chlorinated-pool but not in those using the ozone-treated pool
|
Font-Ribera et al. 2019 (94)
|
Chlorinated-pool (NCl3 mean concentration: 473
µg/m3)
|
Serum CC16; exhaled breath THMs; urinary TCAA; genotoxicity
biomarkers#
|
Creatinine-adjusted urinary TCAA increased by 3.1 μmol/mol
Urine mutagenicity, MN-PBL, MN-Ret and serum CC16 levels remained
unchanged after swimming
No correlation between CBP exposure and MN-PBL, urine mutagenicity and
CC16
Moderate associations observed for MN-Ret and CBP exposure
|